… doxycycline concentrations in tear samples from 10 ophthalmologically normal dogs at
various points after receiving doxycycline … Tear samples were obtained approximately 3 hours …

… symptoms and the health of the tear film. Of course, although oral antibiotics seem to be a …
Additional research is needed to determine if there is a role for doxycycline, minocycline, …

… Results: After oral administration of doxycycline, the drug reached the tear compartment
at concentrations of 45.1–900.7 ng/mL in cats and 45.4–632.0 ng/mL in dogs, representing a …

… They can be administered less often, but they may not reach … however, topical doxycycline
is acidic and can be irritating to … orally administered doxycycline is secreted into the tear film …

… is a frequently used therapeutic option for patients with MGD when mechanical treatment
modalities are not sufficient to reach … are poorly lipophilic and therefore do not reach high tissue …

… oral administration of doxycycline results in detectable tear film concentrations in dogs
reaching … Oral doxycycline administration only achieves a tear concentration of 0.43 μg/mL 9 to …

… tear film levels not being detectable with 100 mg dosing of … ) that the oral administration of
doxycycline and minocycline should … That these antibiotics can actually reach the conjunctival …

… tear film. The depleted meibum results in increased tear evaporation, tear hyperosmolarity,
tear film … concentration level in the tears might not reach an inhibitory concentration with oral …

… can present with additional findings including ocular surface inflammation, changes to the
tear film … CF staining did not reach statistical significance (p=0.262 and p=0.414, respectively). …

… gelatinases and collagenases, which can degrade the extracellular matrix contributing to …
There is scant evidence on the behavior of these cytokines on the tear film of ocular rosacea …